Factors affecting the development of alopecia areata in children

Abstract

The article presents an analysis of modern domestic and foreign publications on the research of the etiology and pathogenesis of the alopecia areata in children. The article brings up the information on the incidence of this type of alopecia in the population, its relationship with heredity, immune and environmental factors. According to generalized literary data, the authors focus on the importance of the role of violations in the lipid peroxidation system and antioxidant protection in the development of the nest alopecia. According to the authors, these processes lead to violations of the function of organs and systems which is reflected in the state of local blood flow and the functional parameters of the skin. The article indicates the literature data on the role of microcirculation violations in the development of the alopecia areata, as well as the pathophysiological mechanisms of its development in children with vitamin D deficiencies The results of a study on the mechanisms for the development of the alopecia areata in children indicate that when conducting children with this pathology, it is necessary to envisage individual approach taking into account the local blood flow, functional parameters of the skin, concomitant pathology, level of vitamin D in the blood and violations in the antioxidant protection system.