DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome-Reference-Cited by-同舟云学术

DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome

Published:2021-06-15 Issue:12 Volume:131 Page:
ISSN:1558-8238
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:

Author:

Tang Xiao-Yan,Xu Lei^ORCID,Wang Jingshen,Hong Yuan^ORCID,Wang Yuanyuan,Zhu Qian,Wang Da,Zhang Xin-Yue,Liu Chun-Yue,Fang Kai-Heng,Han Xiao,Wang Shihua^ORCID,Wang Xin^ORCID,Xu Min,Bhattacharyya Anita^ORCID,Guo Xing^ORCID,Lin Mingyan^ORCID,Liu Yan^ORCID

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Link

https://www.jci.org/articles/view/135763/files/pdf

Reference63 articles.

1. Modelling and rescuing neurodevelopmental defect of D own syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21

2. Development of the Superior Temporal Neocortex Is Anomalous in Trisomy 21

3. Defects in Embryonic Neurogenesis and Initial Synapse Formation in the Forebrain of the Ts65Dn Mouse Model of Down Syndrome

4. Serial quantitative CT analysis of brain morphometrics in adult Down's syndrome at different ages

5. The neurobiologie consequences of down syndrome

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