Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens-Reference-Cited by-同舟云学术

Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens

Published:2023-12-15 Issue:24 Volume:133 Page:
ISSN:1558-8238
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:

Author:

Schlabach Michael R.,Lin Sharon,Collester Zachary R.,Wrocklage Christopher,Shenker Sol,Calnan Conor,Xu Tianlei^ORCID,Gannon Hugh S.,Williams Leila J.^ORCID,Thompson Frank^ORCID,Dunbar Paul R.,LaMothe Robert A.,Garrett Tracy E.,Colletti Nicholas,Hohmann Anja F.,Tubo Noah J.,Bullock Caroline P.,Le Mercier Isabelle,Sofjan Katri,Merkin Jason J.,Keegan Sean,Kryukov Gregory V.^ORCID,Dugopolski Caroline,Stegmeier Frank,Wong Karrie,Sharp Fiona A.,Cadzow Louise,Benson Micah J.

Funder

KSQ Therapeutics

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Link

https://www.jci.org/articles/view/163096/files/pdf

Reference56 articles.

1. Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

2. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

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4. Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

5. Supercharging adoptive T cell therapy to overcome solid tumor–induced immunosuppression

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