Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice
Author:
Funder
National Institute of Health United States
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/153724/files/pdf
Reference55 articles.
1. Mechanisms and disease consequences of nonalcoholic fatty liver disease
2. Selective versus Total Insulin Resistance: A Pathogenic Paradox
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4. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production
5. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ
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