Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins
Author:
Funder
National Cancer Institute
National Institutes of Health
Giorgio Foundation
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/139807/files/pdf
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1. Neurofibromas in NF1: Schwann Cell Origin and Role of Tumor Environment
2. Induction of Abnormal Proliferation by Nonmyelinating Schwann Cells Triggers Neurofibroma Formation
3. Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells
4. Cells of Origin in the Embryonic Nerve Roots for NF1-Associated Plexiform Neurofibroma
5. Perinatal or Adult Nf1 Inactivation Using Tamoxifen-Inducible PlpCre Each Cause Neurofibroma Formation
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