Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis
Author:
Funder
National Institute of Allergy and Infectious Diseases
Acerta Pharma, B.V.
Ernest S. Bazley Foundation
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/138448/files/pdf
Reference56 articles.
1. Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis
2. Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group
3. Desensitization regimens for drug allergy: state of the art in the 21st century
4. Absence of Tec Family Kinases Interleukin-2 Inducible T cell Kinase (Itk) and Bruton's Tyrosine Kinase (Btk) Severely Impairs FcϵRI-dependent Mast Cell Responses
5. The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells
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