Targeting the CALR interactome in myeloproliferative neoplasms
Author:
Funder
Leukemia and Lymphoma Society
NIH Clinical Center
National Cancer Institute
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/122703/files/pdf
Reference37 articles.
1. Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
2. SomaticCALRMutations in Myeloproliferative Neoplasms with NonmutatedJAK2
3. Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation
4. Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage
5. Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis
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