ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models
Author:
Funder
Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg
Deutsche Krebshilfe
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/126345/files/pdf
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1. CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
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3. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
4. The B-cell tumor–associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
5. Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
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