Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis
Author:
Funder
National Institute of Allergy and Infectious Diseases
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/134251/files/pdf
Reference44 articles.
1. Defining the clinical course of multiple sclerosis: The 2013 revisions
2. Chronic Progressive Multiple Sclerosis – Pathogenesis of Neurodegeneration and Therapeutic Strategies
3. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study
4. The sphingosine-1-phosphate receptor: A novel therapeutic target for multiple sclerosis and other autoimmune diseases
5. Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial
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1. Human regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in multiple sclerosis;Frontiers in Immunology;2024-04-30
2. Effect of siponimod on lymphocyte subsets in active secondary progressive multiple sclerosis and clinical implications;Journal of Neurology;2024-04-17
3. Peripheral memory B cells in multiple sclerosis vs. double negative B cells in neuromyelitis optica spectrum disorder: disease driving B cell subsets during CNS inflammation;Frontiers in Cellular Neuroscience;2024-02-07
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