Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
Author:
Funder
National Institutes of Health
U.S. Department of Veterans Affairs
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/167790/files/pdf
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1. Osteoporosis
2. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
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4. Denosumab in Postmenopausal Women with Low Bone Mineral Density
5. Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL*
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