Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells
Author:
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/140273/files/pdf
Reference68 articles.
1. Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
2. Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia
3. Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate
4. The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly
5. Contingent Phosphorylation/Dephosphorylation Provides a Mechanism of Molecular Memory in WASP
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1. Controlled WASp activity regulates the proliferative response for Treg cell differentiation in the thymus;European Journal of Immunology;2024-02-14
2. Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction;Frontiers in Immunology;2023-04-17
3. Understanding immunoactinopathies: A decade of research on WAS gene defects;Pediatric Allergy and Immunology;2023-04
4. A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers;2022-11-25
5. Actin Retrograde Flow Regulated by the Wiskott–Aldrich Syndrome Protein Drives the Natural Killer Cell Response;Cancers;2022-08-02
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