MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

Author:

Chen Jiayu,Zheng Qizhi,Hicks Jessica L.,Trabzonlu LeventORCID,Ozbek Busra,Jones Tracy,Vaghasia Ajay M.,Larman Tatianna C.ORCID,Wang RulinORCID,Markowski Mark C.,Denmeade Sam R.,Pienta Kenneth J.ORCID,Hruban Ralph H.ORCID,Antonarakis Emmanuel S.ORCID,Gupta Anuj,Dang Chi V.,Yegnasubramanian SrinivasanORCID,De Marzo Angelo M.ORCID

Funder

National Cancer Institute

U.S. Department of Defense

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference104 articles.

1. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

2. Mitochondria and cancer

3. The Hallmarks of Aging

4. Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single-cell resolution

5. Detection of mitochondrial DNA mutations in pancreatic cancer offers a “mass”-ive advantage over detection of nuclear DNA mutations;Jones;Cancer Res,2001

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