Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine-Reference-Cited by-同舟云学术

Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine

Published:2024-04-30 Issue:11 Volume:9 Page:
ISSN:2379-3708
Container-title:JCI Insight
language:en
Short-container-title:

Author:

Senkpeil Leetah,Bhardwaj Jyoti,Little Morgan R.,Holla Prasida,Upadhye Aditi^ORCID,Fusco Elizabeth M.^ORCID,Swanson Phillip A.,Wiegand Ryan E.,Macklin Michael D.,Bi Kevin,Flynn Barbara J.,Yamamoto Ayako,Gaskin Erik L.,Sather D. Noah^ORCID,Oblak Adrian L.,Simpson Edward^ORCID,Gao Hongyu,Haining W. Nicholas,Yates Kathleen B.,Liu Xiaowen,Murshedkar Tooba,Richie Thomas L.^ORCID,Sim B. Kim Lee,Otieno Kephas,Kariuki Simon^ORCID,Xuei Xiaoling^ORCID,Liu Yunlong^ORCID,Polidoro Rafael B.,Hoffman Stephen L.^ORCID,Oneko Martina,Steinhardt Laura C.,Schmidt Nathan W.,Seder Robert A.,Tran Tuan M.

Funder

Doris Duke Charitable Foundation

National Institute of Allergy and Infectious Diseases

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

Publisher

American Society for Clinical Investigation

Link

https://insight.jci.org/articles/view/167408/files/pdf

Reference67 articles.

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4. Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

5. Immunization of Man against Falciparum and Vivax Malaria by Use of Attenuated Sporozoites *

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1. Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials;The Lancet Infectious Diseases;2024-08

2. Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission;Biochemical Society Transactions;2024-05-16