A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis-Reference-Cited by-同舟云学术

A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis

Published:2011-11-01 Issue:11 Volume:121 Page:4322-4331
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:J. Clin. Invest.

Author:

Varadarajan Navin,Julg Boris,Yamanaka Yvonne J.,Chen Huabiao,Ogunniyi Adebola O.,McAndrew Elizabeth,Porter Lindsay C.,Piechocka-Trocha Alicja,Hill Brenna J.,Douek Daniel C.,Pereyra Florencia,Walker Bruce D.,Love J. Christopher

Publisher

American Society for Clinical Investigation

Subject

General Medicine

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2. HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

3. HIV-1-specific IFN- /IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells

4. Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

5. High-Programmed Death-1 Levels on Hepatitis C Virus-Specific T Cells during Acute Infection Are Associated with Viral Persistence and Require Preservation of Cognate Antigen during Chronic Infection

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