High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector-Reference-Cited by-同舟云学术

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High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector

Published:2008-04-01 Issue:4 Volume:118 Page:1502-1510
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:J. Clin. Invest.

Author:

Zhang Xiao-Bing,Beard Brian C.,Trobridge Grant D.,Wood Brent L.,Sale George E.,Sud Reeteka,Humphries R. Keith,Kiem Hans-Peter

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference42 articles.

1. GENE THERAPY: Twenty-First Century Medicine

2. Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

3. Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy

4. Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

5. Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

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