IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6-Reference-Cited by-同舟云学术

IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

Published:2006-05-01 Issue:5 Volume:116 Page:1310-1316
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:J. Clin. Invest.

Author:

Yen David,Cheung Jeanne,Scheerens Heleen,Poulet Frédérique,McClanahan Terrill,Mckenzie Brent,Kleinschek Melanie A.,Owyang Alex,Mattson Jeanine,Blumenschein Wendy,Murphy Erin,Sathe Manjiri,Cua Daniel J.,Kastelein Robert A.,Rennick Donna

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference41 articles.

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2. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.

3. T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

4. Antibodies to interleukin 12 abrogate established experimental colitis in mice.

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