Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease
Author:
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Reference24 articles.
1. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
2. T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease
3. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
4. T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
5. Impaired Bone Marrow Microenvironment and Immune Function in T Cell Protein Tyrosine Phosphatase–deficient Mice
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1. Inflammation versus regulation: how interferon-gamma contributes to type 1 diabetes pathogenesis;Frontiers in Cell and Developmental Biology;2023-05-24
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3. Common polymorphisms of protein tyrosine phosphate non-receptor type 2 gene are not associated with risk of Crohn’s disease in Indian;World Journal of Gastrointestinal Pathophysiology;2022-07-22
4. Modulation of PTPN2/22 Function by Spermidine in CRISPR-Cas9-Edited T-Cells Associated with Crohn’s Disease and Rheumatoid Arthritis;International Journal of Molecular Sciences;2021-08-18
5. PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells;Cell Reports;2020-07
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