Tumors recycle glucocorticoids to drive Treg-mediated immunosuppression
Author:
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/173141/files/pdf
Reference12 articles.
1. Steroid hormone regulation of immune responses in cancer
2. Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
3. Glucocorticoid imprints a low glucose metabolism onto CD8 T cells and induces the persistent suppression of the immune response
4. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
5. Tumors induce de novo steroid biosynthesis in T cells to evade immunity
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