Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice
Author:
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Reference35 articles.
1. Dysregulation of the TSC-mTOR pathway in human disease
2. Complexity of the TOR signaling network
3. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
4. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
5. TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
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