The mechanosensory channel PIEZO1 functions upstream of angiopoietin/TIE/FOXO1 signaling in lymphatic development
Author:
Funder
National Institutes of Health
Publisher
American Society for Clinical Investigation
Link
https://www.jci.org/articles/view/176577/files/pdf
Reference55 articles.
1. Lymphatics thrive on stress: mechanical force in lymphatic development
2. Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion
3. Piezo1 incorporates mechanical force signals into the genetic program that governs lymphatic valve development and maintenance
4. Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
5. A Novel Homozygous Missense Mutation of PIEZO1 Leading to Lymphatic Malformation-6 Identified in a Family With Three Adverse Pregnancy Outcomes due to Nonimmune Fetal Hydrops
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1. Lymphatic System Development and Function;Current Cardiology Reports;2024-08-22
2. Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema;Journal of Clinical Investigation;2024-05-30
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