Linear stability for a free boundary problem modeling the growth of tumor cord with time delay

Author:

Zhou Haihua1,Liu Yaxin2,Wang Zejia2,Song Huijuan2

Affiliation:

1. School of Mathematics and Statistics, Hengyang Normal University, Hengyang 421010, China

2. School of Mathematics and Statistics, Jiangxi Normal University, Nanchang 330022, China

Abstract

<abstract><p>This paper was concerned with a free boundary problem modeling the growth of tumor cord with a time delay in cell proliferation, in which the cell location was incorporated, the domain was bounded in $ \mathbb{R}^2 $, and its boundary included two disjoint closed curves, one fixed and the other moving and a priori unknown. A parameter $ \mu $ represents the aggressiveness of the tumor. We proved that there exists a unique radially symmetric stationary solution for sufficiently small time delay, and this stationary solution is linearly stable under the nonradially symmetric perturbations for any $ \mu &gt; 0 $. Moreover, adding the time delay in the model leads to a larger stationary tumor. If the tumor aggressiveness parameter is bigger, the time delay has a greater effect on the size of the stationary tumor, but it has no effect on the stability of the stationary solution.</p></abstract>

Publisher

American Institute of Mathematical Sciences (AIMS)

Subject

Applied Mathematics,Computational Mathematics,General Agricultural and Biological Sciences,Modeling and Simulation,General Medicine

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