Topological indices of novel drugs used in blood cancer treatment and its QSPR modeling-Reference-Cited by-同舟云学术

Topological indices of novel drugs used in blood cancer treatment and its QSPR modeling

Published:2022 Issue:7 Volume:7 Page:11829-11850
ISSN:2473-6988
Container-title:AIMS Mathematics
language:
Short-container-title:MATH

Author:

Nasir Sumiya¹,ul Hassan Awan Nadeem²,Farooq Fozia Bashir³,Parveen Saima²

Affiliation:

1. Department of Mathematics and Natural Sciences, College of sciences and Human Studies, Prince Mohammad Bin Fahd University, Khobar 31952, Saudi Arabia

2. Department of Mathematics, Government College University Faisalabad, Pakistan

3. Department of Mathematics and statistics, Imam Mohammad Ibn Saud Islamic University, Riyadh 11564, Saudi Arabia

Abstract

<abstract> <p>A topological index is a real number obtained from the chemical graph structure. It can predict the physicochemical and biological properties of many anticancer medicines like blood, breast and skin cancer. This can be done through degree-based topological indices.. In this article, the drugs, azacitidine, buslfan, mercaptopurine, tioguanine, nelarabine, etc. which are used in order to cure blood cancer are discussed and the purpose of the QSPR study is to determine the mathematical relation between the properties under investigation (eg, boiling point, flash point etc.) and different descriptors related to molecular structure of the drugs. It is found that topological indices (TIs) applied on said drugs have a good correlation with physicochemical properties in this context.</p> </abstract>

Publisher

American Institute of Mathematical Sciences (AIMS)

Subject

General Mathematics

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