<i>Cassia auriculata</i> L.–A mini review of phytochemical compounds and their antidiabetic mechanisms

Abstract

<abstract> <p><italic>Cassia auriculata</italic> is an important medicinal herb traditionally used for the treatment and management of diabetes. Scientific research has reported some bioactivities related to traditional roles that include antihyperglycemic and antihyperlipidemic, which could inhibit onset of diabetes. Our aim was twofold: To review the presence of phytochemical compounds in plant extracts and to perform an <italic>in-papyro</italic> evaluation of their antidiabetic potential. A detailed literature survey was carried out for evaluating metabolic syndrome-related medicinal bioactivities and antidiabetic activity from specific compounds of <italic>C. auriculata</italic>. We uncovered a wide range of medicinal uses of <italic>C. auriculata</italic> in Ayurveda and Sri Lankan medicinal traditions and cultures. Many of the compounds in <italic>C. auriculata</italic> extracts have already been reported for their specific antidiabetic, hypoglycemic, and hypolipidemic activities, which exhibited positive effects on neuro, renal, and liver support. In conclusion, our findings suggested that the phytocomposition of <italic>C. auriculata</italic> could be attributed to the presence of antidiabetic activity through various mechanisms.</p> </abstract>