Simple and Objective Evaluation Items for the Prognosis and Mortality of Delirium in Real‐World Clinical Practice: A Preliminary Retrospective Study

Author:

Shibuya Yuzuru1,Kobayashi Ryota2,Numazawa Takuma1,Toyoshima Toyoki1,Hayashi Hiroshi3,Sone Toshimasa3,Morioka Daichi2,Suzuki Akihito2,Kawakatsu Shinobu14

Affiliation:

1. Department of Psychiatry Nihonkai General Hospital Sakata Japan

2. Department of Psychiatry Yamagata University School of Medicine Yamagata Japan

3. Department of Occupational Therapy Fukushima Medical University School of Health Sciences Fukushima Japan

4. Department of Neuropsychiatry Aizu Medical Centre Fukushima Medical University Aizuwakamatsu Japan

Abstract

ObjectiveIdentifying factors associated with poor outcomes in patients with delirium is important for predicting prognosis. This retrospective study developed an easy and objective cognitive function measurement scale that can predict the prognosis and mortality related to delirium.MethodsFifty‐five patients aged ≥65 years and diagnosed with delirium were included. Objective data regarding attention and orientation related to time and place were extracted from their medical records during the first consultation, and in total, six points were evaluated. The patients were categorized into high and low cognitive function (LCF) groups. The severity at the first visit and 1‐week post‐treatment was evaluated using the Clinical Global Impressions‐Severity scale. Outcomes (survival or death) at 6 months from the initial visit were evaluated by reviewing medical records.ResultsAlthough the Clinical Global Impressions‐Severity score at the first visit was not significantly different between the two groups, 1 week after treatment, it was significantly lower in the high cognitive function (HCF) group than in the LCF group. Regarding the outcome (survival or death) after 6 months, the LCF group had significantly higher mortality than the HCF group. A multivariate logistic regression analysis revealed the same result (OR = 17.049, 95% CI = 2.415–120.373, p = 0.004).ConclusionA simple cognitive assessment of attention and orientation may help predict unfavorable outcomes, including mortality, in patients with delirium.

Publisher

American Psychiatric Association Publishing

Subject

General Engineering

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