Ivermectin in the treatment of COVID-19- friend or foe?

Author:

Schellack N.1,Padayachee N.2,Schellack G.2

Affiliation:

1. University of Pretoria

2. University of the Witwatersrand

Publisher

Medpharm Publications

Reference58 articles.

1. World Health Organization (WHO). Influenza novel coronavirus (2019-nCoV) and coronavirus disease (COVID-19) pandemic [Internet]. Available from: https:// www.who.int/influenza/en/; https://www.who.int/emergencies/diseases/ novel-coronavirus-2019; https://www.who.int/dg/speeches/detail/whodirectorgeneral-s-remarks-at-the-media-briefingon-2019-ncov-on-14-january-2021; and https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-astheyhappen. Accessed 14 Jan 2021.

2. National Institute for Communicable Diseases (NICD). COVID-19 [Internet]. Available from: https://www.nicd.ac.za/diseasesa-z-index/covid-19/. Accessed 12 13 & 14 Jan 2021.

3. Safety of high-dose ivermectin: a systematic review and meta-analysis;Navarro M;J Antimicrobial Chemother.,2020

4. Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond;Boldescu V;Nat Rev Drug Discov.,2017

5. Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus;Wagstaff KM;Biochem J.,2012

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