Combination oral contraceptives – a practice-guided overview of everyday problems and their solutions

Author:

Wolmarans DW1,Brand L1,Steyn SF1

Affiliation:

1. North-West University

Abstract

Combination oral contraceptives (COCs) are some of the most commonly prescribed drugs for women between the ages of 15–451 and while they are accepted to be safe and highly effective, their use is often associated with a number of minor sideeffects. Considering the limited nature of this review, a detailed overview of the complete clinical profile of COCs falls beyond the current scope. Rather, we will focus on the most frequently reported side-effects of COCs that do not necessitate treatment withdrawal. Adverse effects that require immediate withdrawal of therapy are usually related to deep vein thrombosis (DVT) and other cardiovascular events, malignancies or hepatic pathology2 and would require a more in-depth review.

Publisher

Medpharm Publications

Reference23 articles.

1. Croke LM. CDC Updates Recommendations for Contraceptive Use. American Family Physician. 2017;95(2):125-126.

2. Melmed S, Polonsky K, Larsen PR, Kronenberg H. Williams Textbook of Endocrinology. Elsevier Health Sciences; 2015.

3. Taggart TC, Eaton NR, Keyes KM, Hammett JF, Ulloa EC. Oral contraceptive use is associated with greater mood stability and higher relationship satisfaction. Neurology, Psychiatry and Brain Research. 2018;30:154-162. https://doi.org/10.1016/j.npbr.2018.10.004.

4. DiPiro JT, Talbert RL, Yee GC, et al. Pharmacotherapy: A Pathophysiologic Approach. 9th ed. New York: McGraw-Hill Medical; 2014.

5. Hodgen GD. Methods of extended use oral contraception. 2007, Google Patents.

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