Optimal Management of Severe/Refractory Asthma

Author:

Pakhale Smita12,Mulpuru Sunita1,Boyd Matthew1

Affiliation:

1. The Ottawa Hospital at the University of Ottawa, Ottawa, ON, Canada.

2. Ottawa Hospital Research Institute, Ottawa, ON, Canada.

Abstract

Asthma is a chronic inflammatory disease of the airways, affecting approximately 300 million people worldwide. Asthma results in airway hyperresponsiveness, leading to paroxysmal symptoms of wheeze, cough, shortness of breath, and chest tightness. When these symptoms remain uncontrolled, despite treatment with high doses of inhaled and ingested corticosteroids, asthmatic patients are predisposed to greater morbidity and require more health care support. Treating patients with severe asthma can be difficult and often poses a challenge to physicians when providing ongoing management. This clinical review aims to discuss the definition, prevalence and evaluation of severe asthmatics, and provides a review of the existing pharmacologic and non-pharmacologic treatment options.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine

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