Uroplakin III Is a Highly Specific and Moderately Sensitive Immunohistochemical Marker for Primary and Metastatic Urothelial Carcinomas

Author:

Kaufmann Olaf1,Volmerig Jan1,Dietel Manfred1

Affiliation:

1. Institute of Pathology, Charité University Hospital, Berlin, Germany.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference16 articles.

1. Wu X, Lin J, Walz T, et al. Mammalian uroplakins: a group of highly conserved urothelial differentiation-related membrane proteins. J Biol Chem. 1994;269:13716-13724.

2. Yu J, Lin J, Wu X, et al. Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins. J Cell Biol. 1994;125:171-182.

3. Koss LG. The asymmetric unit membrane of the epithelium of the urinary bladder of the rat: an electron microscopic study of a mechanism of epithelial maturation and function. Lab Invest. 1969;21:154-168.

4. Alroy J, Weinstein RS. Intraepithelial, asymmetric-unit-membrane plaques in mammalian urinary bladder. Anat Rec. 1980;197:75-83.

5. Moll R, Wu X, Lin J, et al. Uroplakins, specific membrane proteins of urothelial umbrella cells, as histological markers of metastatic transitional carcinomas. Am J Pathol. 1995;147:1383-1397.

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