Evaluation of HER-2/neu Immunohistochemical Assay Sensitivity and Scoring on Formalin-Fixed and Paraffin-Processed Cell Lines and Breast Tumors

Author:

Rhodes Anthony,Jasani Bharat,Anderson Elizabeth,Dodson Andrew R.,Balaton André J.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference30 articles.

1. Pegram MD, Lipton A, Hayes DF, et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185 monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol. 1998;16:2659-2671.

2. Slamon D, Leyland-Jones B, Shak S, et al. Addition of Herceptin (humanized anti-Her2 antibody) to first line chemotherapy for Her2 overexpressing metastatic breast cancer (Her2+/MBC) markedly increases anticancer activity: a randomised multinational controlled phase III trial [abstract]. Proc Am Soc Clin Oncol. 1998;17:98A. Abstract 377.

3. Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-over-expressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol. 1999;17:2639-2648.

4. Allred DC, Swanson PE. Testing for erbB-2 by immuno-histochemistry in breast cancer. Am J Clin Pathol. 2000;113:171-175.

5. Clark GM. Prognostic and predictive factors. In: Harris JR, Lippman ME, Morrow M, et al, eds. Diseases of the Breast. Philadelphia, PA: Lippincott-Raven; 1996:461-485.

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