Streptomyces BAC Cloning of a Large-Sized Biosynthetic Gene Cluster of NPP B1, a Potential SARS-CoV-2 RdRp Inhibitor
Author:
Affiliation:
1. Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea
2. Department of Biological Engineering, Inha University, Incheon 22212, Republic of Korea
Funder
National Research Foundation of Korea
Publisher
Korean Society for Microbiology and Biotechnology
Subject
Applied Microbiology and Biotechnology,General Medicine,Biotechnology
Reference28 articles.
1. Actinomycetes: still a source of novel antibiotics
2. Heterologous expression-facilitated natural products’ discovery in actinomycetes
3. A Single Biosynthetic Gene Cluster Is Responsible for the Production of Bagremycin Antibiotics and Ferroverdin Iron Chelators
4. Engineering actinomycetes for biosynthesis of macrolactone polyketides
5. Post-PKS Tailoring Steps of a Disaccharide-Containing Polyene NPP in Pseudonocardia autotrophica
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1. Generation of New Glycoanalogues of Polyene Antibiotics by Synthetic Biology—Testing Current Technical Boundaries;SynBio;2024-01-04
2. The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 Pandemic;Viruses;2023-11-25
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