Mutational analysis of the affinity maturation of antibody 48G7
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference42 articles.
1. Modulation of antibody binding affinity by somatic mutation;Allen;Int. J. Cancer. Supplement,1988
2. Three-dimensional structure determination of an anti-2-phenyloxazolone antibody;Alzari;EMBO J.,1990
3. Molecular events during maturation of the immune response to oxazolone;Berek;Nature,1985
4. Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody V-H region;Casson;J. Immunol.,1995
5. Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen;Casson;J. Expt. Med.,1995
Cited by 46 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Optimal immunization cocktails can promote induction of broadly neutralizing Abs against highly mutable pathogens;Proceedings of the National Academy of Sciences;2016-10-24
2. Synthesis, Characterization, and Optimization for in Vivo Delivery of a Nonselective Isopeptidase Inhibitor as New Antineoplastic Agent;Journal of Medicinal Chemistry;2015-02-12
3. Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis;Journal of Allergy and Clinical Immunology;2014-09
4. The intrinsic cysteine and histidine residues of the anti-Salmonella antibody Se155-4: a model for the introduction of new functions into antibody-binding sites;Protein Engineering Design and Selection;2014-05-14
5. Mutational Analysis of 48G7 Reveals that Somatic Hypermutation Affects Both Antibody Stability and Binding Affinity;Journal of the American Chemical Society;2013-06-26
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3