Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution

Author:

Ding Jianping,Das Kalyan,Hsiou Yu,Sarafianos Stefan G,Clark Arthur D,Jacobo-Molina Alfredo,Tantillo Chris,Hughes Stephen H,Arnold Edward

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference92 articles.

1. A sequence motif in many polymerases;Argos;Nucl. Acids Res.,1988

2. Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations;Arnold;Nature,1992

3. Targeting HIV reverse transcriptase for anti-AIDS drug design;Arnold;Drug Des. Discov.,1996

4. Interaction of retroviral reverse transcriptase with template-primer duplexes during replication;Arts;Prog. Nucl. Acid Res. Mol. Biol.,1998

5. Mutational studies of human immunodeficiency virus type 1 reverse transcriptase;Bakhanashvili;FEBS Letters,1996

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