Implications for function and therapy of a 2.9 å structure of binary-complexed antithrombin
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference33 articles.
1. A hinge region mutation in C1-inhibitor (Ala436→Thr) results in nonsubstrate-like behavior and in polymerization of the molecule;Aulak;J. Biol. Chem.,1993
2. Conversion of antithrombin from an inhibitor of thrombin to a substrate with reduced heparin affinity and enhanced conformational stability by binding of a tetradecapeptide corresponding to the P1 to P14 region of the putative reactive bond loop of the inhibitor.
3. Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen VI (187 Asn→Asp);Bruce;J. Clin. Invest.,1994
4. Biological implications of a 3 Å structure of dimeric antithrombin;Carrell;Structure,1994
5. Probing serpin reactive loop conformations by proteolytic cleavage;Chang;Biochem. J.,1996
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