Evidence against the Current Hypothesis of “Gene Dosage Effects” of Trisomy 21: ets-2, Encoded on Chromosome 21” Is Not Overexpressed in Hearts of Patients with Down Syndrome

Author:

Greber-Platzer Susanne,Schatzmann-Turhani Dritan,Wollenek Gregor,Lubec Gert

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference9 articles.

1. Molecular and stochiastic basis of congenital heart disease in Down Syndrome;Korenberg,1995

2. Genes, embryogenesis and Down Syndrome;Kola,1995

3. Simplified RT/PCR quantitation of gene transcripts in cultured neuroblastoma (SN 49) and microglial (BV-2) cells using capillary electrophoresis and laser-induced fluorescence detection;Personett;Electrophoresis,1996

4. Schatzmann-Turhani, D. Greber-Platzer, S. Cairns, N. Lubec, G. Determination of the protooncogene ets-2 gene transcript in human brain at the attogram level by the use of competitive RT-PCR, Amino Acids

5. Single-step method of RNA isolation by acid gunidinium thiocyanate-phenol-chloroform extraction;Chomczynski;Analyt Biochem,1987

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