IL-12 INDUCES SDS-STABLE CLASS II αβ DIMERS IN MURINE DENDRITIC CELLS

Author:

Grohmann U,Orabona C,Bianchi R,Belladonna M.L,Fioretti M.C,Puccetti P

Publisher

Elsevier BV

Subject

Molecular Biology,Hematology,Biochemistry,Immunology,Immunology and Allergy

Reference14 articles.

1. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding;Germain;Nature,1991

2. Amino acid residues on the I-Akα-chain required for the binding and stability of two antigenic peptides;Nelson;J Immunol,1996

3. The class II MHC I-Ag7molecules from non-obese diabetic mice are poor peptide binders;Carrasco-Marin;J Immunol,1996

4. IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells;Bianchi;J Immunol,1996

5. A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state;Grohmann;J Immunol,1997

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