Does A2E, a Retinoid Component of Lipofuscin and Inhibitor of Lysosomal Degradative Functions, Directly Affect the Activity of Lysosomal Hydrolases?

Author:

Bergmann Marion,Schütt Florian,Holz Frank G.,Kopitz Jürgen

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference24 articles.

1. Isolation of intact lysosomes from human RPE-cells and effect of A2-E on the integrity of the lysosomal membrane. ARVO abstract;Bellmann;Invest. Ophthlamol. Vis. Sci.,2000

2. Effects of increasing numbers of phagocytic inclusions on retinal pigment epithelial cells in culture: a model for aging;Boulton;Br. J. Ophthalmol.,1986

3. Age pigment structure;Eldred;Nature,1993

4. Lipofuscin and other lysosomal storage deposits in the retinal pigment epithelium;Eldred,1998

5. The lipid peroxidation theory of lipofuscinogenesis cannot yet be confirmed;Eldred;Graefes. Arch. Clin. Exp. Ophthalmol.,1991

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