Mutation of N304 to Leucine in Streptomyces clavuligerus Deacetoxycephalosporin C Synthase Creates an Enzyme with Increased Penicillin Analogue Conversion-Reference-Cited by-同舟云学术

Mutation of N304 to Leucine in Streptomyces clavuligerus Deacetoxycephalosporin C Synthase Creates an Enzyme with Increased Penicillin Analogue Conversion

Published:2001-09 Issue:2 Volume:287 Page:507-513
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Chin Hong Soon,Sim Janet,Sim Tiow Suan

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference23 articles.

1. The β-lactam antibiotics: past, present, and future;Demain;Antonie Van Leeuwenhoek,1999

2. Structure of a cephalosporin synthase;Valegard;Nature,1998

3. The enzyme involved in biosynthesis of penicillin and cephalosporin; their structure and function;Cooper;Bioorg. Med. Chem.,1993

4. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes;Roach;Nature,1995

5. The substrate specificity of deacetoxycephalosporin C synthase (“expandase”) of Streptomyces clavuligerus is extremely narrow;Maeda;Enzyme Microb. Technol.,1995

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