Cytotoxic Mechanism of XK469: Resistance of Topoisomerase IIβ Knockout Cells and Inhibition of Topoisomerase I-Reference-Cited by-同舟云学术

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Cytotoxic Mechanism of XK469: Resistance of Topoisomerase IIβ Knockout Cells and Inhibition of Topoisomerase I

Published:2001-02 Issue:4 Volume:280 Page:1155-1160
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Snapka Robert M.,Gao Hanlin,Grabowski Dale R.,Brill David,Chan Kenneth K.,Li Ligeng,Li Gloria C.,Ganapathi Ram

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference18 articles.

1. DNA topoisomerase poisons as antitumor drugs;Liu;Annu. Rev. Biochem.,1989

2. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication;Snapka;Mol. Cell. Biol.,1986

3. Eukaryotic DNA topoisomerase IIβ;Austin;BioEssays,1998

4. Murine transgenic cells lacking DNA topoisomerase IIβ are resistant to acridines and mitoxantrone: Analysis of cytotoxicity and cleavable complex formation;Errington;Mol. Pharmacol.,1999

5. XK469, a selective topoisomerase IIβ poison;Gao;Proc. Natl. Acad. Sci. USA,1999

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1. Exploring the effects of topoisomerase II inhibitor XK469 on anthracycline cardiotoxicity and DNA damage;Toxicological Sciences;2024-01-30

2. Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells;Biochemistry and Biophysics Reports;2017-07

3. Rapid and efficient synthesis of 2-substituted-tetrahydropyrido[3,4-b]quinoxalines using TDAE strategy;Tetrahedron Letters;2012-05

4. Contemporary Challenges in the Design of Topoisomerase II Inhibitors for Cancer Chemotherapy;Chemical Reviews;2012-03-08

5. Topoisomerase II Inhibitors: Chemical Biology;Cancer Drug Discovery and Development;2011-08-26

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