An Enzymatically Active Chimeric Protein Containing the Hydrophilic Form of NADPH-Cytochrome P450 Reductase Fused to the Membrane-Binding Domain of Cytochrome b5

Author:

Gilep Andrei A.,Guryev Oleg L.,Usanov Sergey A.,Estabrook Ronald W.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference16 articles.

1. Cytochrome P450, Structure, Mechanism, and Biochemistry;Ortiz de Montellano,1987

2. Cytochrome b5 reduction by NADPH-cytochrome P-450 reductase;Enoch;J. Biol. Chem.,1979

3. Structural features of liver microsomal NADPH-cytochrome P450 reductase. Hydrophobic domain, hydrophilic domain, and connecting region;Black;J. Biol. Chem.,1982

4. The role of microsomal cytochrome b5 in the metabolism of ethanol, drugs and the desaturation of fatty acids;Ozols;Ann. Clin. Res.,1976

5. The high-level expression in Escherichia coli of the membrane-bound form of human and rat cytochrome b5 and studies on their mechanism of function;Holmans;Arch. Biochem. Biophys.,1994

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