Unrestrained 5 ns molecular dynamics simulation of a cisplatin-DNA 1,2-GG adduct provides a rationale for the NMR features and reveals increased conformational flexibility at the platinum binding site-Reference-Cited by-同舟云学术

Unrestrained 5 ns molecular dynamics simulation of a cisplatin-DNA 1,2-GG adduct provides a rationale for the NMR features and reveals increased conformational flexibility at the platinum binding site

Published:2001-12 Issue:5 Volume:314 Page:1227-1243
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Elizondo-Riojas Miguel-Angel,Kozelka Jiřı́

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference54 articles.

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4. The major adduct of the antitumor drug cis-DDP with DNA bends the duplex by 40 °C toward the major groove;Rice;Proc. Natl Acad. Sci. USA,1988

5. A d(GpG)-platinated decanucleotide duplex is kinked - an extended NMR and molecular mechanics study;Herman;Eur. J. Biochem.,1990

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