A Second Dihydroorotate Dehydrogenase (Type A) of the Human Pathogen Enterococcus faecalis: Expression, Purification, and Steady-State Kinetic Mechanism-Reference-Cited by-同舟云学术

A Second Dihydroorotate Dehydrogenase (Type A) of the Human Pathogen Enterococcus faecalis: Expression, Purification, and Steady-State Kinetic Mechanism

Published:2000-05 Issue:1 Volume:377 Page:178-186
ISSN:0003-9861
Container-title:Archives of Biochemistry and Biophysics
language:en
Short-container-title:Archives of Biochemistry and Biophysics

Author:

Marcinkeviciene Jovita,Jiang Wenjun,Locke Gregory,Kopcho Lisa M.,Rogers M.John,Copeland Robert A.

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference32 articles.

1. Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro

2. Leflunomide Inhibits Pyrimidine de Novo Synthesis in Mitogen-stimulated T-lymphocytes from Healthy Humans

3. The Immunosuppressive Metabolite of Leflunomide Is a Potent Inhibitor of Human Dihydroorotate Dehydrogenase

4. Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide

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