Heterologous Expression of Cytochrome P450 2D6 Mutants, Electron Transfer, and Catalysis of Bufuralol Hydroxylation: The Role of Aspartate 301 in Structural Integrity-Reference-Cited by-同舟云学术

Heterologous Expression of Cytochrome P450 2D6 Mutants, Electron Transfer, and Catalysis of Bufuralol Hydroxylation: The Role of Aspartate 301 in Structural Integrity

Published:2001-09 Issue:2 Volume:393 Page:255-261
ISSN:0003-9861
Container-title:Archives of Biochemistry and Biophysics
language:en
Short-container-title:Archives of Biochemistry and Biophysics

Author:

Hanna Imad H.,Kim Mi-Sook,Guengerich F.Peter

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference54 articles.

1. Identification of molecular aggregates containing glycoproteins III, J, K (carboxypeptidase H), and H (Kex2-related proteases) in the soluble and membrane fractions of adrenal medullary chromaffin granules.

2. Cytochrome P450: Structure, Mechanism, and Biochemistry;Capdevila,1995

3. Cytochrome P450: Structure, Mechanism, and Biochemistry;Kagawa,1995

4. Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms

5. Biochemistry and molecular biology of the human CYP2C subfamily

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