Analysis of the Cytotoxic Properties of Linoleic Acid Metabolites Produced by Renal and Hepatic P450s

Author:

Moran Jeffery H.,Mitchell Lex A.,Bradbury J.Alyce,Qu Wei,Zeldin Darryl C.,Schnellmann Rick G.,Grant David F.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference58 articles.

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2. Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS;Bylund;Anal. Biochem.,1998

3. Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes;Bylund;J. Pharmacol. Exp. Ther.,1998

4. Cytochrome P450 arachidonic acid epoxygenase: Stereochemical characterization of epoxyeicosatrienoic acids;Capdevila;Methods Enzymol.,1991

5. Renal vasodilator activity of 5,6-epoxyeicosatrienoic acid depends upon conversion by cyclooxygenase and release of prostaglandins;Carroll;J. Biol. Chem.,1993

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