Diazinon Is Activated by CYP2C19 in Human Liver

Author:

Kappers Wendela A.,Edwards Robert J.,Murray Stephen,Boobis Alan R.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference29 articles.

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2. Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens;Boobis;Br. J. Clin. Pharmacol.,1980

3. Inhibition and inactivation of constitutive cytochromes P450 in rat liver by parathion;Butler;Mol. Pharmacol.,1993

4. Biotransformation of parathion in human liver: Participation of CYP3A4 and its inactivation during microsomal parathion oxidation;Butler;J. Pharmacol. Exp. Ther.,1997

5. Inhibition patterns of brain acetylcholinesterase and hepatic and plasma aliesterases following exposures to three phosphorothionate insecticides and their oxons in rats;Chambers;Fundam. Appl. Toxicol.,1993

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