Uterine Responsiveness to Estradiol and DNA Methylation Are Altered by Fetal Exposure to Diethylstilbestrol and Methoxychlor in CD-1 Mice: Effects of Low versus High Doses

Author:

Alworth L.C.,Howdeshell K.L.,Ruhlen R.L.,Day J.K.,Lubahn D.B.,Huang T.H-M.,Besch-Williford C.L.,vom Saal F.S.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference62 articles.

1. 17 beta-Estradiol has a biphasic effect on gh cell growth;Amara;Endocrinology,1983

2. Number of CpG islands and genes in human and mouse;Antequera;Proc. Natl. Acad. Sci. USA,1993

3. Dose levels of 0.01–0.2 μg/kg/day diethylstilbestrol are not suitable for use as a positive control in endocrine toxicity studies;Ashby;Regul. Toxicol. Pharmacol.,1999

4. ATSDR, 1994, Toxicological Profile for Methoxychlor, Agency for Toxic Substances and Disease Registry, U.S. Department of Health and Human Services, Atlanta.

5. Relaxin influences the growth of MCF-7 breast cancer cells. Mitogenic and antimitogenic action depends on peptide concentration;Bigazzi;Cancer,1992

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