Selective Rep-Cap Gene Amplification as a Mechanism for High-Titer Recombinant AAV Production from Stable Cell Lines
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference37 articles.
1. Gene transfer into the CNS using recombinant adeno-associated virus: Analysis of vector DNA forms resulting in sustained expression;Clark;J. Drug Targeting,1999
2. In vivoexpression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector;During;Gene Ther.,2000
3. Adeno-associated virus-mediated gene transfer to the brain: Duration and modulation of expression;Lo;Hum. Gene Ther.,1999
4. Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors;Koeberl;Proc. Natl. Acad. Sci. USA.,1997
5. Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors;Snyder;Nat. Genet.,1997
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