Differential Modulation of Sodium Channel Gating and Persistent Sodium Currents by the β1, β2, and β3 Subunits

Author:

Qu Y.,Curtis R.,Lawson D.,Gilbride K.,Ge P.,DiStefano P.S.,Silos-Santiago I.,Catterall W.A.,Scheuer T.

Publisher

Elsevier BV

Subject

Cell Biology,Cellular and Molecular Neuroscience,Molecular Biology

Reference38 articles.

1. Modal gating of Na+ channels as a mechanism of persistent Na+ current in pyramidal neurons from rat and cat sensorimotor cortex;Alzheimer;J. Neurosci.,1993

2. A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel;Auld;Proc. Natl. Acad. Sci. USA,1990

3. A rat brain Na+ channel α subunit with novel gating properties;Auld;Neuron,1988

4. A molecular basis for gating mode transitions in human skeletal muscle Na+ channels;Bennett;FEBS Lett.,1993

5. Mice lacking sodium channel β2 subunits have reduced sodium channel densities and negative shifts in the votage dependence of channel inactivation;Bharucha;Soc. Neurosci.,2000

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