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Preclinical Study of Tacrolimus Ointment for Prevention of Its Systemic Absorption in Atopic Dermatitis Model Mice According to Their Skin Conditions

  • Published:2017-09-10 Issue:9 Volume:43 Page:477-491
  • ISSN:1346-342X
  • Container-title:Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
  • language:en
  • Short-container-title:Jpn. J. Pharm. Health Care Sci.

Author:

Hazama Yutaro1,Uchida Wataru1,Maekawa Toshihisa1,Miki Ryotaro1,Oshima Shinji1,Egawa Yuya1,Hosoya Osamu1,Seki Toshinobu1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Josai University

Publisher

Japanese Society of Pharmaceutical Health Care and Sciences

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference44 articles.

1. 1) Simon D, Vassina E, Yousefi S, Kozlowski E, Braathen LR, Simon HU, Reduced dermal infiltration of cytokine-expressing inflammatory cells in atopic dermatitis after short-term topical tacrolimus treatment, J Allergy Clin Immunol, 2004, 114, 887-895.

2. 2) Schuller E, Oppel T, Bornhövd E, Wetzel S, Wollenberg A, Tacrolimus ointment causes inflammatory dendritic epidermal cell depletion but no Langerhans cell apoptosis in patients with atopic dermatitis, J Allergy Clin Immunol, 2004, 114, 137-143.

3. 3) Panhans-Groß A, Novak N, Kraft S, Bieber T, Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506), J Allergy Clin Immunol, 2001, 107, 345-352.

4. 4) Ring J, Alomar A, Bieber T, Deleuran M, Fink-Wagner A, Gelmetti C, Gieler U, Lipozencic J, Luger T, Oranje AP, Schäfer T, Schwennesen T, Seidenari S, Simon D, Ständer S, Stingl G, Szalai S, Szepietowski JC, Taïeb A, Werfel T, Wollenberg A, Darsow U; European Dermatology Forum (EDF); European Academy of Dermatology and Venereology (EADV); European Federation of Allergy (EFA); European Task Force on Atopic Dermatitis (ETFAD); European Society of Pediatric Dermatology (ESPD); Global Allergy and Asthma European Network (GA2LEN), Guidelines for treatment of atopic eczema (atopic dermatitis) Part i, J Eur Acad Dermatology Venereol, 2012, 26, 1045-1060.

5. 6) Reitamo S, Rissanen J, Remitz A, Granlund H, Erkko P, Elg P, Autio P, Lauerma AI, Tacrolimus ointment does not affect collagen synthesis: results of a single-center randomized trial, J Invest Dermatol, 1998, 111, 396-398.

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