Importance of Lipophilicity and Polar Surface Area of Compounds on the Transport Activity of Intestinal H<sup>+</sup>/tertiary Amine Antiporter-Reference-Cited by-同舟云学术

Importance of Lipophilicity and Polar Surface Area of Compounds on the Transport Activity of Intestinal H⁺/tertiary Amine Antiporter

Published:2015 Issue:4 Volume:41 Page:236-243
ISSN:1346-342X
Container-title:Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
language:en
Short-container-title:Jpn. J. Pharm. Health Care Sci.

Author:

Ishida Kazuya¹,Horie Asuka¹,Matsuba Emi¹,Watanabe Yuri¹,Fukao Miki¹,Hashimoto Yukiya¹

Affiliation:

1. Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

Publisher

Japanese Society of Pharmaceutical Health Care and Sciences

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

https://www.jstage.jst.go.jp/article/jjphcs/41/4/41_236/_pdf

Reference14 articles.

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2. 2) Mizuuchi H, Katsura T, Ashida K, Hashimoto Y, Inui K, Diphenhydramine transport by pH-dependent tertiary amine transport system in Caco-2 cells, Am J Physiol Gastrointest Liver Physiol, 2000, 278, G563-G569.

3. 3) Masago M, Takaai M, Sakata J, Horie A, Ito T, Ishida K, Taguchi M, Hashimoto Y, Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells, Biol Pharm Bull, 2010, 33, 1407-1412.

4. 4) Ishida K, Horie A, Nishimura M, Taguchi M, Fujii N, Nozawa T, Inoue H, Hashimoto Y, Variability of bioavailability and intestinal absorption characteristics of bisoprolol, Drug Metab Pharmacokinet, 2013, 28, 491-496.

5. 5) Fukao M, Ishida K, Horie A, Taguchi M, Nozawa T, Inoue H, Hashimoto Y, Variability of bioavailability and intestinal absorption mechanisms of metoprolol, Drug Metab Pharmacokinet, 2014, 29, 162-167.

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