Simultaneous Determination of 17 Residual Monomers in Adhesives by Gas Chromatography–Mass Spectrometry

Abstract

Adhesives are indispensable raw materials in the assembly of electronics and electrical equipment. Residual monomers in adhesives pose a threat to humans and the environment. Therefore, quantitative analysis of residual monomers in adhesives is extremely important. In this paper, a gas chromatography–mass spectrometry (GC–MS) method was established and validated for the simultaneous quantification of 17 residual monomers in adhesives, including 15 acrylates and two acrylamides. The ultrasonic extraction conditions were optimized and determined based on the extraction effect and cost. In addition, the matrix effect of residual monomers in adhesives is widespread. A matrix matching calibration standard with high sensitivity, accuracy, and stability was adopted to reduce the matrix effect on quantification. This method can be used for the determination of multiple residual monomers in adhesives.